(1) Mature red blood corpuscles are membrane bound and normally devoid of a nucleus, nucleolus , cell organelles, and inclusions.(2) As the cells separated their chromosomes, the nucleolus also appeared to segregate asymmetrically between mother and daughter cells, with the majority in the mother.(3) No specialized techniques, such as morphometry for assessing nucleolar size or special stains for mucin, were employed.(4) The LTR probe uniformly labels the chromosome arms except at the telomeres, nucleolar organizing regions, and centromeres, where the signal is lacking.(5) The tumor cells were arranged in trabecular and solid patterns with nuclear pleomorphism, prominent nucleoli , and scant basophilic cytoplasm.(6) Proteins synthesized through the interaction of nuclear, nucleolar , and cytoplasmic nucleic acids are first concentrated in the sacs of the Golgi apparatus in the form of granules or droplets.(7) Microscopically, large neoplastic lymphoid cells with prominent nucleoli and frequent mitotic figures occlude small vessel lumina.(8) Active transcription of ribosomal DNA is required in all organisms for both nucleolar formation and ribosome biogenesis.(9) In addition to nucleolar prominence, multiple nucleoli and nucleolar margination have also been suggested as diagnostic criteria for prostate cancer.(10) Some cells had conspicuous nucleoli , and others had cytoplasmic clearing.
